From my observation Manchester united can't win Liverpool and it seems united fans has also lost hope in the match cause the noise makers I know will always shout for victory but they're just quite, what's the problem with united they lack team work and orderliness at some extend I doubt if united players train before coming out to play cause why will Maguire be everywhere and when did he start playing as a striker, I will love united to win but the strength of united is just too weak.
Manchester United got a big shock in Champions League that can trigger a domino effect on their next performances. However it won't always happen and sometimes, a team in trouble can strongly bounce back but we won't know how Manchester United will perform in Premier League after disappointed in Champions League.
They generally don't have good quality compares to Liverpool so if Liverpool play at their full strength and ability, don't give gifts with mistakes to Manchester United, three points will belong to Liverpool.
As for Liverpool I doubt if Liverpool will stay long in the top I don't know why but I doubt cause have not even seen their best performance and they can't even withstand Arsenal for now am not sure Arsenal will let Liverpool win, Liverpool still have castle boys to face and I believe this time Newcastle will come prepared.
Staying at top of Premier League is not easy but Liverpool are not a weak team and they actually experienced that feeling as well as pressure at the leading position many times. They won't have much problems to stay there but I agree that there will be a lot of challenge from other competitors like Arsenal and Manchester City.