Napoli have often experienced quite significant defeats from Barcelona when they met in European matches, but I think Napoli can breathe a sigh of relief because the current Barcelona is not as strong as the Barcelona that Napoli previously faced, head to head it could be said if Barcelona is quite superior, but for Now we can see how Napoli in the last few years has become a fairly strong club in the league and is capable of becoming a champion contender, I think for the next match head to head is not a guarantee to be able to underestimate Napoli.
You are correct, going by their H2H statistics, Barcelona bhas always won Napoli in most of their Europa meetings but I. Their most recent meeting, they had a draw and Barcelona won the second time, going by that statistics it will be expected that same should happen because the last time was a 4-0 flawless victory leaving Napoli with no goal.
I think this time it's most likely they will end the game in a draw as neither teams are in a very good form currently they are both having some drawdown in their domestic leagues but before this match I think they will be having some little time to put their selves together so as to get an better performance, Barcelona looks more promising because they have got the experience on how well to win Napoli except they will present a weak form which Napoli can take advantage of els it's more likely a draw or Barcelona will maintain their winning record against Napoli as usual.