@OP you can replace your transactions, but make sure the next transactions you use the same inputs like your previous transactions.
so every node that uses the default size of 300MB will drop the transactions that have fees of less than 23.2sat/vb but nodes use custom mempool size so the transaction will likely stay longer because it stays in some nodes.
But not all transactions that exceed the mempool size will be dropped, your transactions could be re-broadcast by your wallet or other nodes.