I saw that after failing in the Champions League, Newcastle's condition was getting worse and it was very difficult for them to perform optimally to win the match. If you look at the number of players who have suffered injuries, it is true, as you said, that it is not surprising that Newcastle are again disappointing. If this does not change, Newcastle's condition will become even more difficult and it is possible that they will be further left behind at the bottom of the standings.
It is predictable because Newcastle United just have their first season in Champions League after some decades. They don't have experience to decentralize their resources for Premier League and Champions League. From coach, staffs to players, they all dont' have this experience and it's no surprise to see they tried hard in Champions League, failed there while they got some consequences for Premier League like low ranking and some player injuries.
For the Champions League, perhaps there is not much we can comment on because Newcastle is in a group with teams that are much more experienced and mature in the Champions League, so it is difficult for them to qualify for the last 16 of the Champions League As a result, they lost their top five position after experiencing several defeats and the impact of injuries to several players also hit Newcastle, causing them to lose a lot of points in the previous match.
Last season they didn't take part in many competitions so they could balance the matches they played. The coach is also not very experienced in handling crucial matches, so when a number of their players are not available, it makes it difficult for Newcastle to rotate.