Indeed, Borussia Dortmund's experience in the UCL league is no longer in doubt, they have participated in the UCL league every year, even though they did not become UCL champions, they often trouble the big teams. In fact, this season they managed to advance to the last 16 from the hell group.
But even so, Borussia Dortmund should not underestimate PSV in the first leg of the round of 16, especially since the first leg will be played at PSV's home ground, of course this will be a motivation for them to beat Borussia Dortmund in front of their own supporters. Apart from that, PSV this season has appeared very impressive in the domestic league, so far they have not been defeated, of course this will make it difficult for Borussia Dortmund to win in the first leg. So my prediction is that the first leg of PSV vs Borussia Dortmund will end in a draw.
Last season, Dortmund experienced quite significant changes after mid-season. so, let's see whether Dortmund will experience another change in improving its performance. we'll find out soon, once the Bundesliga restarts and the Champions League round of 16 competition is held. so, for now we can only speculate and assume. let's flashback to several previous Dortmund matches, Edin Terzic's squad did not get full points in their 6 matches in various competitions. so, it is very natural that bookies favor PSV in the first leg. because their performance shows that Dortmund is not in their best condition even though they have experience in the Champions League compared to the opposing team.
On the contrary, PSV should not be underestimated and I agree with that. in their domestic league, they are the top team. in fact, in 16 matches PSV did not suffer a single defeat. during the Champions League group phase, PSV was able to hold Arsenal to a draw when playing at home. so for this match, I will not rush into making decisions or assume too far. especially if we refer to the betting exchange, for the time being PSV is the favorite.
however, Dortmund is a unique team, they will provide fierce resistance when they meet a stronger team. especially, in crucial matches. in this round of 16, Dortmund will not underestimate their opponent. therefore, Terzic will prepare his team to perform at its best. well, because this match still has a time lag, we'll just follow every development, especially when playing in the Domestic League. for betting or results, for me it is still too early to speculate.