I think there are two parts to the story. The first one is having a successful business that generates profits. It doesn't really matter if these profits are being generated in Fiat or crypto currencies. We can always just trade our profit into the currency or coin that we need. The same goes for paying expenses and taxes, any liquid crypto coin can be converted back to fiat to pay the bills. The second part to the story is what we are doing with our profits. Assuming that our business has enough capital and we are not interested in reinvesting our profits, or planning new projects, we can just trade or hodl cryptos. It's a basic calculation to compare the return we make each year with our crypto portfolio, and how much return our business generates. As long as we don't lose any money in trading that is necessary to run our business, I don't see problem with. Also treating the two separately helps to focus on the profitability and to maximize our profits.