Liverpool star Mohamed Salah will not be present in next match against Tottenham. This will not reduce Liverpool's chances of winning, but it will reduce its chances of scoring the largest number of goals. On this basis, I would bet on the chance of "under 2.5 goals" could be as profitable as the match against Arsenal.
I also think it will be a difficult match for Liverpool since Wataru Endo will not be present either due to his participation in the Asian Championship with his country. Since the chances of winning decrease, betting on the total goals of the match will be better.
Liverpool will not have Mohamed Salah but Tottenham will not have Son Heung-Min. They are both very important players for two teams but Liverpool have more attacking star players who can cover the absence of Salah. In contrast, Tottenham don't have such abundant substitutions and replacements like Liverpool and Son Heung-Min simply is almost can not replaced in their club.
Logically Liverpool will still be a stronger team in the match and they in theory will have higher chance to win the match than Tottenham.