I don't think that it's a good combo. I prefer just to play games and have fun or overcome difficulties. Mixing it with crypto or money at all will make it less fun IMO.
Yes absolutely. Games are designed for refreshment of the mind. We play games in order to cheer up our mood from daily workload. Now if you integrate Bitcoins or money in games, then here also we will take stress and cannot enjoy the games. From OP’s point of view it seems that he is asking about Gambling casino games. Here you can bet with cryptos or real money for playing games and can make profits from it.