I've reluctantly made withdrawals because I needed urgent financial aid to situations that I did not make plans for. I would not say I really regret it, but I would say that I'm thankful that I had a place where I could get money to clear out myself. At a time, it was two choices for me, to either take a loan or sell off some bitcoins. Taking loans would yield interest that may make it difficult to pay, so I decided to sell off some bitcoins and work towards replacing them later (which I am doing now). If I sold bitcoins for some unimportant reason or expenses, I will be regretting by now, but because I sold some for a better reason, I do not regret it.