The best thing Guardiola can do is to start finding a plan to not be dependent on some players like Haaland or De Bruyne.
Imagine Manchester City playing in the Champions League and in an important game like the final match of this season but both players De Bruyne and Haaland get injured, with the current situation of this team, they will definitely lose and this is not good for them.
Pep Guardiola is a professional coach and he knows what he has to do to maintain the physicality of his players, such as using these players only in important matches against big clubs and if he only plays against small clubs, Guardiola will usually use Haaland or De Bruyne in the second half when there is left. just a few minutes so it's not too risky to use the player with little time.
We don't need to worry, in the Champions League, there are many elite clubs that have great coaches, even though injuries are always a nightmare, a coach always tries to ensure the quality of the players' performance.
You don't need to worry, in the final round we will see De Bruyne appear with Haaland to fight for the CL title.
Only now it seems that Guardiola has to be more careful in managing his players because there are still many obstacles that must be faced and if Guardiola cannot look after the players' performance it will have bad consequences.