Inter is the favorite to progress to the quarter-finals compared to Atletico Madrid, but however Atletico Madrid is also a strong team. Atletico Madrid has players who can be relied on in defense and attack, they are dangerous for any team and the round of 16 match against Inter will certainly be very tight.
Inter failed last season in the final against Manchester City, but I don't expect Inter to get to the final again this season. I tend to expect Atletico Madrid to progress to the next round rather than Inter, but Inter's performance so far has been too difficult for any team to stop. We'll see what happens between Inter and Atletico Madrid in the first leg, it shouldn't be easy to predict.
Inter Milan is better prepared this season to go far in the Champions League this season. Inter Milan will be quite superior when facing Atletico Madrid, even though in the context of these two teams being equally strong, But Inter Milan performance is better than Atletico Madrid this season. Moreover, the first leg will be an advantage for Inter Milan because they play in front of their supporters or at the San Siro. Yes, even though this is a home match, Inter Milan must play more carefully because Griezmann and Morata are quite sharp this season, they are able to unbalance the opponent's defense with their skill in handling the ball in front of the goal.
Apart from that, in this case I saw that Inter Milan had a good rally when they met the Laliga team. This match will definitely steal the attention of many football fans, especially Inter Milan fans, where they hope that their idol team can repeat the success like last season, which was able to reach the final. For Inter Milan, they really hope that Martinez and Thuram can perform better in the Champions League because this season the competition is quite tight in the Champions League.