The clash between Inter and Atletico Madrid is going to be quite interesting.

Inter are favoured at Giuseppe Meazza in the first game of course. But I don't see a big difference between these two teams. The only difference seen is their positions in their domestic leagues at the moment. But this would be really misleading while comparing these two teams.
Because maybe Atletico Madrid aren't in any title competition in the La Liga but they are still a very strong team now. They did a really good job against Real Madrid in a game recently as well. I expect a solid resistance from them in the first game even if they lose. My score prediction is like a 1-0 or 2-1 win by Inter.

Intermilan was always very consistent in kicking out la liga club and this is also making the situation even worst for atletico madrid coz intermilan is at the peak performance. It means that if the chance owned by intermilan to beat it is very high. I think that intermilan will be playing safely in this match.
I prefer to see inter use the defensive combined with the direct counter attack against atletico madrid. Intermilan is having stronger defensive line compared to the other club like real madrid. Intermilan has very big chance to win the game soon.
Btts is most likely to happen soon consider atletico madrid will not also miss opportunity to gather three points to make sure it will be in the safe zone to face the second leg. Securing first leg with huge margins will guarantee the club to win the second leg much higher.
It makes sense to see intermilan has been favored compared to the real atletico madrid. Im feeling that if everything will be going much better than before. I hope that it will be going so well for intermilan.