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Winning with a pretty fantastic score certainly made Klopp happy and Liverpool also celebrated when Liverpool were able to beat Brentford. However, if Liverpool is experiencing an unfortunate fate such as the injuries to the three players you mentioned, of course this is a big worry for Liverpool, who at this time can still be a candidate to win the Premier League. Klopp must be able to handle this well in the next few matches because considering that these three players are players that Klopp has relied on very often this season.
Injuries to important players are a serious problem for any coach, including Jurgen Klopp. Darwin Nunez, Diogo Jota and Curtis Jones are three very important mainstay players in the Liverpool squad, two of them are strikers and this is not good news because the competition between Liverpool and Manchester City will become even tighter.
If Manchester City wins the match against Chelsea today, then Liverpool will obviously be under pressure because Manchester City will likely win the match against Brentford too. If Manchester City wins both matches, then they will lead the standings and make Liverpool drop to second place. Of course it wasn't what Liverpool fans expected, but stopping Manchester City's run is very difficult when they are at their best.
That's absolutely true because of the outstanding match left for Manchester city to play. I doubt Chelsea FC would even be able to hold them tonight to a draw because with De Bruyne back and the midfield in complete lock, the Chelsea attackers would have to rely on mostly set pieces and quick counter if they are to secure any goal.