If I'm unsure of the person's sex, I refer to them as "they". That cuts across my posts here. Some people don't like it when you misappropriate their gender while others don't give it a second thought. They see it as nothing. On the picture thing on the profile, many would think a dude is making use of his wife's or gf's picture on their profile there.
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Oh yeah, I have also switched to 'they/them' and been using it for years in the forum. The quoted story was during my early years hence the "I used to"

I understand people not liking it when someone misgendered them but make sure you have explicitly said your preferred pronouns first. The gender neutral they/them is frankly relatively new to be widely adopted all over the world and some folks are just not in a progressive environment. From the communities I've been on alone, a lot are actually willing learn once you teach them.