Manchester City can win the Premier League title with or without Keven De Bruyne. Liverpool, on the other hand, has excellent attackers who can produce; they can play effectively and score goals even without Salah. As a result, they may win the league. However, since Arsenal defeated both Manchester City and Liverpool this season, I will also include them in the title race. They have an impressive squad that can win the league.
Kevin contributed a lot for Manchester City and their five Premier League titles in last six seasons. Manchester City have a strong squad and very abundant good players as substitutions and it's logic to think they can win Premier League this season without Kevin. The fact is they were not too far from Liverpool and Arsenal without Kevin previous months but it's reasonable to expect Manchester City will become stronger in next months. After returning from his injury and recovery, he has contributed some goals and assists for them and it's signal that Manchester City will have lot of expectation on Kevin.
It cannot be denied that Kevin De Bruyne's contribution is quite big for the Manchester City team, even though the team does not depend on Kevin alone because they also have suitable substitute players, but we can see for ourselves this season when Kevin was injured and Manchester City's performance declined slightly.
If someone says that Manchester City can win the Premier League without Kevin, it is true, but it must also be admitted that the performance of the Manchester City team will decline slightly without Kevin.