Even without Höjlund, Manchester United will win this match. I mean, if they want to be in the top four, they have to win. In recent games, even if they concede goals, they score a lot of goals and win. That's why defensive mistakes are not a big problem.
I think Aston Villa will also win, so the points difference will not decrease. Nottingham Forest cannot pose a serious threat. The team that has lost 3 games in a row at Villa Park wouldn't allow the 4th one to happen. Also Watkins is in great shape.