So far, Manchester united has had difficulty beating Manchester city because statistically, Manchester united has only been able to achieve 1 win in 5 meetings against Manchester city. The enthusiasm of the supporters will certainly be able to raise enthusiasm for the players, but in this meeting I think Manchester city is really aiming to win to be able to overtake liverpool. For this reason, Manchester united has a relatively small chance of beating Manchester city.
Normally, derby or rival matches are difficult to predict because anything can happen but this game looks pretty easy. It doesn't mean Manchester United don't stand a chance but Man City are too superior at the moment. Manchester United is in shambles at the moment.
When you look at both teams you'll know that Manchester City is more motivated to win because they're fighting for the league and it's matches like this that determine how much you want the league.
Man United on the other hand are just trying to make it to the top 4, a position I doubt they'll make this season.
With De Bruyne fit and firing, I think this is a straight win for Manchester City. De Bruyne on his day can win the match on his own. He creates and he scores goals out of nothing. Add that to the deadly partnership he has with Halland. Man United are going to work extra hard if they want to get at least a draw in that game.