Good news: On the Bullish "Big Rally" BTC side, making money with Alt/USD is easy, and sometimes you can also gain much more from Alt/BTC going up too.
It only means that for every pair on this market, anyone can make money. But I'd stick to BTC/USD for this moment and I'd stack with that for more. While I trade some alts so that I'd get some money as well from those trades, I'll make sure that I'll have more of it so that I can stick to my plan until the top price of Bitcoin shows.
The way they are accumulating bitcoin the exchanges will run out of bitcoin very soon which will create a supply shock.
We will get some clue and signs when exchange are halting withdrawals or when they limit specific amounts for withdrawals.