I've got upwards of 10BTC to sell, and intend to withdraw my proceeds as Canadian dollars. The biggest issues I see for this size of transaction are (a) withdrawal fees, and (b) daily/monthly withdrawal limits.
Any recommendations on where to start?
If you have no problem with KYC, you can use centralized exchanges and after KYC, you will have no issue with limit on withdrawal, it will be bigger than your 10 BTC.
Just remember about risk of KYC and centralized exchanges.