Well, it seems to be the hardest match to watch this week.
Atletico Madrid vs Barcelona
In fact, both of them also entered the UCL quarter-finals. Of course, both of them have very passionate motivation and enthusiasm, at least to prove who is the best between the two.
You are right that Atletico Madrid against FC Barcelona is the toughest match of the week in the Spanish La Liga. There recent meetings have always produced few goals probably because both teams are conscious of their defending. Now the trick is, Barcelona have won Atletico Madrid by 1-0 in each of the last three meetings, going by that Barcelona is expected to maintain same record. But it is football where anything can happen, Atletico Madrid can still do magic to turn the recent history around.
Maybe a fairly fair result is a draw. but I don't think either of them would hope so. Of course they hope that a big win will be theirs. Yes, just wait and see how the two teams that have qualified for the UCL will compete for victory in La Liga.
A draw is likely in the match and it will not be a bad result for either sides. Barcelona are not playing in their best form so I will not expect them to win Atletico Madrid that may not have been doing so great but is definitely a side to beat.