Arteta and Arsenal players know what is at stake when they play Manchester City, and I think they will be ready to face Manchester City. If Arteta takes time to study the Liverpool vs Manchester City match last week, he can know the tactics to use that will make Kevin de Bruyne not be a threat against them.
Arsenal also actually managed to take the lead in their last meeting with City. it might be even more difficult for Arsenal because they have to play at City's home ground. it's not easy to get a win from City.
but there is no other option for Arsenal to beat City at this time. If they are unable, maybe City can defend their championship title again last season.
I still hope that the battle between the top 3 teams in the standings will last until the end of the season. and it will be very exciting for the Premier League.