In the upcoming match, Arsenal will visit the Etihad stadium and if we look at their match history, we can see that it is very difficult for Arsenal to beat Manchester City at the Etihad stadium. Even though in the first meeting this season Arsenal managed to beat Manchester City with a score of 1-0, in the second meeting I think Manchester City will be the favorite to win it. These two teams are competing in the standings and their meeting will probably be fiercer than their first meeting this season.
I think if Manchester City manages to beat Arsenal then Arsenal has no chance of competing for the title this season. For this reason, Arteta does not want to repeat his mistakes this season, so this season they want to target the title, so the match between the two will probably be quite tough because they are both aiming for victory. On the other hand, Liverpool must also focus on their target of becoming champions, and Liverpool can take advantage of the final results of their two competitors as motivation for them to get 3 points when facing Brighton.
The reason why in the first meeting Arsenal managed to beat Man City was because they were without De Bruyne who was injured and the match also took place at Arsenal's home ground. Now Man City's strength is so complete and they have the advantage of playing at home so I think it will be much more difficult for Arsenal to beat Man City. The tension of the match is also different because it is a fairly important match for the start of the title this season so both of them will play quite carefully.
If Arsenal loses then their chances of winning the English league will be smaller, unless they can hold a draw or win the match. This will be a big match in the English league because there are bets on who will lose or who will win. But even so, I am more confident that Man City will win the match because they are playing in front of their own crowd.