I don't know how many people want Manchester City to lose at home to Arsenal. Manchester City are basically favorites to win the match, but there is no guarantee they can win it even though the probability of winning is quite high. The match will be very tiring for both teams especially because both are in good form.
Beating Arsenal may have become a normal job for Pep Guardiola since coaching Manchester City, but I just don't want Pep Guaridola to underestimate Arsenal who are fighting to win their first title with Arteta. Liverpool and Arsenal could stop Manchester City's title dominance this season, but Manchester City doesn't seem to be giving up that easily.
I think this is a typical case when only City fans want a City victory, but the fans of all other teams, even Liverpool, want an Arsenal victory

Dominant clubs are annoying, and if their dominance is based on dirty dealings, then this increases the irritation tenfold. We can hope that City players will be on their minds already in the game against Real Madrid and Arsenal will earn at least a draw in this game.
I will not use the games played previous season to judge how Manchester City vs arsenal game will be because right now arsenal is a strong team and they have been doing better. I just know Manchester City have more advantage of winning since it is a home game for them, I won't be surprise if Manchester City wins against arsenal but I know the game won't be easy for Manchester City because arsenal is tough. From the performance of arsenal this season I don't think Manchester City will easily defeat them, if Manchester City wins against arsenal that means they are lucky to grab victory.