Atalanta's performance in the UEL was relatively good because he was able to reach the quarter-finals and against an EPL team which was a big obstacle for Atalanta in this round, Liverpool is clearly superior in this match because Liverpool's performance is very strong this season and he will try hard so that there is no the team that stopped them from reaching the final. Liverpool will eliminate teams in every round somehow, Kloop is very ambitious to get the UEL trophy at the end of his time and that will happen if Liverpool continues to appear consistent and doesn't make any mistakes.
I even think that Atalanta has met an opponent who is not equal to them in the quarter-finals of the Europa League this time because after all Liverpool will still be the favorite for many people if the opponent is Atalanta. So this is a very real obstacle for Atalanta to advance to the next round because as you said, Liverpool will not allow any team to beat them now in order to enter the semi-finals of the Europa League. So I wouldn't be surprised if Atalanta lost the quarter-final match because it wouldn't be a significant surprise.
In terms of quality, Liverpool is indeed better than Atalanta this season and it cannot be denied that Liverpool will be very favored to advance to the semifinals, but the Liverpool team also cannot completely underestimate Atalanta because in a football match anything is possible to happen and also in terms of quality. Atalanta, which is slumping in its domestic league, is showing a different performance in the Europa League, so Liverpool should be wary of it.
If Atalanta lose it won't be a big surprise because basically they are not favourites, but I'm sure this match will be fierce and Liverpool will win with great difficulty.
And it is also possible for surprises to occur. This is the Europa League where there have always been surprises.