It's strange that the city won't be able to take the trophy this season, given that they've won it several times in a row. The EPL is becoming even more competitive than I expected.
The previous season was relatively easy for Manchester City because it only had Arsenal as a competitor. This time is even tougher than before. It appears that Liverpool is a strong club capable of winning the trophy at any time.
Man City's chances are still great, the match against Arsenal could be key. If they win of course Man City will be ahead of the points, then it's a tough task to keep maintaining by continuing to get points in the remaining matches. But if the final result later draws or loses, then Man City will be more difficult, because they only hope for Arsenal and Liverpool's mistakes in the rest of the next match. De Bruyne's injury does not seem to be a big problem for Pep, they have to maximize the existing players.