Ederson and De Bruyne appear to be injured, at least that's what the news is circulating. If it is certain that the two players above will not join the team in the match against Arsenal, then it is very possible for Arsenal to get points at the Etihad Stadium. It may be difficult, but the opportunities are there and Arsenal need to maximize their ability to take points.
Without Ederson and De Bruyne, Manchester City is not a weak team, but Arsenal can exploit their weaknesses, especially if City loses stability in their midfield. I don't really expect Arsenal to have a high probability of winning on the road, so this means Manchester City tends to be the favourite.
EPL matches becomes boring without the interference of these outstanding players. Everything will worked in due time, everyone needs to be patient becauset the slightest mistakes will give opponents work. Manchester City would have crumbled in performance but overlooking certain sectors. Pep Guardiola knows what to do when it comes to injuries in his squad, he ensured he has good replacement for them and not relenting efforts. Manchester City goalkeeper, Ederson injured, atleast he has good time and represents his s side well enough.