If Kevin De Bruyne do not play in that game, it will be the second time this season where he misses the game against Arsenal. I do not believe that he will not play though, it is very possible that the coach is manipulating the media to have an advantage. Even if KDB does not play, Manchester City are still very strong, because they already used to play without him as they played some games this season without him being present and were still able to win. The two coaches are not strangers, Manchester City are the top choice to win, Arsenal is not underrated.
Kelvin De Bruyne was actually replaced against Liverpool due to tactical reasons as Pep himself confirms this and then he was used in the FA cup tie and wasn’t forced up. Missing the international break was something I see as a precautionary measure from both Belgium and Manchester city, it was to give him more time to heal more and help Manchester City In the closing stage and also go on to stay fit for the Euros in the Summer. So the news coming out now about him missing the Arsenal game is just one of Pep’s mindset or the media just reporting rumors. As at now i am optimistic that he will play the game, same thing with Saka who left the England squad also to stay fit. Both were precautionary measures and will play against each other by the weekend