I think Arsenal and Manchester City are the teams that are not affected by a lot of crowds because they played in front of a lot of fans. As a result of playing this match, they learned how to play under pressure. Even though Manchester City has the advantage, this will be a match that the better team will win.
It has a small or big influence, but it cannot be denied that playing at home makes a team have better motivation and self-confidence, whereas the visiting team will be under a little pressure.
Likewise with Arsenal, even though they are a big team, it cannot be denied that the support of Manchester City fans will make Arsenal's mentality decline a little, especially since this match is very crucial for the two teams who are competing in the race for the Premier League title this season.
Things like this are very common in football and considering that both of them are at the same level, I don't think Arsenal's mentality will waver in the slightest. It's just that Arsenal's winning record at home to Manchester City is not as great as expected and they always experience difficulties when they are the visiting team. But it's still a big game and Arsenal will have to give everything to beat one of their rivals.
On the other hand, Manchester City did not benefit after several of its players had to be absent due to injuries sustained during the international break and this was clearly very detrimental. Time and time again they all performed without problems in the EPL but with one or two matches in the international break everything became chaotic and uncontrollable. Arsenal seems to have had unexpected luck and I am very sure they will be favored with the completeness of their current squad.