Do you want to bet on West Ham reaching the semi-finals or on them winning the individual game? In general, on the one hand, it makes sense to bet against Bayer, because they can’t never lose. But on the other hand, I don’t yet see that such a bet could be made with good odds. Even at home for Bayer, the game quotes are very modest:
1.55 – 4.10 – 6.20
It seems to me that here it is more profitable to take +55% on the favorite’s victory than to look for luck on the side of the outsider.
Quite an interesting match indeed in this case where the two clubs in the country will destroy each other in the Europa League competition.
Seeing the current conditions it is quite natural that Milan are favorites for the first leg where they will play at the San Siro and with more stable conditions but seeing the odds given to Roma I think it's too big and seems too underestimated even though if you look at the situation that is happening now Roma have actually performed quite well under the care of De Rosi at the moment and surely they will provide strong enough resistance when facing Milan despite playing away for the first leg.
I think instead of betting on one of the clubs here I might play it safe by taking a draw as an option even though the risk is quite large in the end when Milan are in very good condition now but it is still a reasonable thing in my opinion when it comes to a draw in this match.