many gambling addicts have lost their minds because their desire to continue gambling overpowers their common sense, hence the importance of "gambling responsibly"
Ironically when there are people who cannot control addiction in gambling, this is just a small example of many gamblers that ended worse and there are some who end their lives because they are in debt when gambling. Gambling is responsible when you are not addicted and when it cannot be controlled, in my opinion it is difficult to be responsible for gambling choices.
The problem is how you put gambling, if done only for fun in spare time is not a problem. But when gambling is done as a substitute for permanent work, this will be far more problematic and it is very difficult to control, the decision is in each of us and as much as possible avoid addiction in gambling.
Gambling addiction is a genuine problem, and as you indicated, it may lead to financial disaster and even suicide. In this instance, they require assistance, which might include regulating the gaming business in such a manner that they are not abused by gambling companies. For example, we may impose limitations on how much money individuals can bet in a certain period of time, or we could force gambling organizations to offer information about the odds of winning. We may also require gaming firms to give responsible gambling training for their staff. Also, to raise awareness about the issues involved, such as the perils of gambling addiction.