I'm new to all this but I'm thinking I will just build a rig with lower power nVidia cards for Scrypt mining since at least the computer can be used for other things and would hold some resale value.
What about Scrypt ASICs? They should draw a lot less power than GPUs.
If your referring to gridseeds, I don't think they're worth it, they won't have a good ROI, as in a couple months the scrypt "ASICS" come out like the titan. If you want to mine, I suggest mining a groestl,scrypt-n,x11, etc. algorithm coin.