If we look at the points, it really won't affect their position. Real Madrid will remain in first place and Barcelona as runner up. However, this is El Classico which is always a prestigious match and a place to show off who is stronger in the match. Always high tension when it comes to Barcelona and Real Madrid. That's why El Classico is always interesting because there is a deep rivalry between the two. 
In my opinion, in this week's El Clasico match, Real Madrid wants to ensure it with a win and doesn't want to delay their climb to the La Liga championship. We know that Real Madrid will still be very busy after successfully qualifying for the semifinals of the Champions League and they don't want their target of winning the La Liga title to hinder them and even though their opponent is Barcelona, they definitely want to beat Barcelona again like in the previous meeting. .....
El Classico against Barcelona is a decisive and also tempting match. There was nothing wrong with either of them when fighting each other. This is El Classico where both Real Madrid and Barcelona always show their total ability.