Actually there should be no problem with auto process of an amount like $50k because casino would always based in your pattern of deposits and withdrawals, so if you are within the range, there should be nothing suspicious about the transaction.
For instance, you are a gambler who deposits $50k to $100k and you made a withdraw of $50k, that should not trigger the system. However, if your range is at $100 to $200 only and you request a withdrawal of $50k, then surely that would alarm the system.
The system will trigger the system only if the user requested withdrawal immediately after depositing them without doing anything wagering because it could be considered as money laundering so it's job of the casino to make sure no one is abusing their platforms. And in other possible scenarios like someone won 50K with $100 bet or something and went to withdrawal will be reviewed to check there is no bugs that were exploited or things like that.