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Barcelona might lost their match El Clasico because they are playing with their rivals who will not give them the chance of winning the match. Also I will say that Real Madrid is more lucky this season than last season, so they had been lucky in most of their matches by winning it even when we don't expect it.
Barcelona is stronger than Valencia, and I don't see how it will be possible for Valencia to win Barcelona, who lost their last match and they are not happy with that defeat. Also if Barcelona did not win this match, they know that Girona might take over the second position from them on the table. This is why it is a most for Barcelona to win Valencia. It will be an easy win for them.
Barcelona's loss in El Clasico was basically not because Real Madrid didn't give Barcelona a chance to win the match, but Barcelona was just unlucky in some of its chances. Real Madrid and Barcelona played equally well in the last El Clasico, but Real Madrid was luckier, especially because Bellingham was finally able to score the winning goal in injury time.
Valencia is not an easy opponent, and Barcelona is also not expected to win easily at home. I think the match will be as good as the previous few matches, but as a team that has squad depth and better performance, Barcelona has the right to hold favorite status at home.