The AML directive is nothing new and was already discussed intensely here.
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... CASPs in the EU won't be able to offer mixing services.
However, it's likely that something like Samourai would not be a CASP under this directive, where CASPs are entities in general which control funds, realize transactions on behalf of customers, or give financial advice. If Samourai only provided a server to receive messages from potential CoinJoin participants, but did not sign these transactions, then it wasn't in control of the funds and also didn't "realize" the transactions.
Anyway, as things stand, I think these are the first steps. The next ones will be to ban all kinds of services that offer privacy, be they mixers, coinjoin services or whatever. The defense of privacy has always been stronger in Anglo-Saxon countries. Nobody in the EU is going to protest strongly about this. In the same way that cash payment limits will continue to fall and even if they do not fall, it does not matter because inflation will do its job. This is in line with the launch of CBDCs.