I guess I should have qualified my comments... those who have a bunch of 7970 cards that they paid $700+ for will consider them unprofitable... that can still mine, but will have much less hope of making back the investment in all likely hood.
The newer cards, even the ATI cards can still work... I probably painted with too wide of a brush with the first comment and no explanation.

But thats the nice thing about GRS, it works really well with old cards! I'm mining with 5870s (~6500 KH/s) and 5970s (~12500 KH/s). They are super energy-efficient if you undervolt them. Best of all, 5870s go for about 70-80 on ebay (in Germany), and I recently snagged two 5970s for 100 each. Very low investment cost, and I'm pretty sure I can even get 50-70% of the money back if I sell the cards in half a year or so.