Do they make more profit than digital banks, CEX exchanges, etc.?
It could be, gambling whether online or offline, is already a billion dollar business.
You just have to look at this forum and see that there are casinos born maybe every month as a business to at least get a piece of that big pie, just a slice and it will be more than enough to make money.
As compare to let's say a crypto exchange, there could be traders around, but it takes skills and technical know how just to make a decent money. Unlike in gambling wherein, some individual from Asia to Africa started to create an account to a online casino and then deposit crypto and starts to play, easy like that and then you have one customer, one potential customer that can get addicted.
While casinos can without a doubt reach a larger audience, as anyone can understand the rules of their preferred games in a matter of minutes, at the same time I think the money that goes into exchanges is many times higher, and this is because most gamblers are indeed responsible, so they only bet a small amount of their income, however traders use a great part of their wealth when trading, so even if there are less people using exchanges, they bring way more money with them.