In my opinion, as long as I'm on the Bitcointalk forum, there isn't a single coin that can challenge Bitcoin, the reason why? Bitcoin is the main key or parent of all coins that have ever existed, with a very high quality of interest and a wide network. While coin memes are just a joke made by a certain group, they don't have a definite totality for the future.
Yeah of course and what we must also consider is the popularity because Bitcoin is the most popular coin and the highest accepted coin by everybody which is very powerful because wherever you go and they mentioned cryptocurrency the first thing they will call is Bitcoin because that's how much people love it and want to go into investing on it, so I don't think there would be a coin that will stand against Bitcoin.