From basic economic principles, if you have a higher capital, you will certainly have higher returns compared to starting with a smaller capital. If you're just chasing returns or expecting a huge profit margin but pay slight attention to how much you use as your capital, even when you make a profit, the extent of your profit will largely depend on how much is your Capital.
REMEMBER
50% profit on $1000 is $500
5% profit on $100,000 is $5000
THE IMPLICATION IS;
Don't chase bigger returns, chase more capital. This is also applicable to How much you invest in Bitcoin and how much profit you can get from it.
So what happens to people that doesn't have enough capital base are you saying they shouldn't set up a business? If I see a business opportunity that's offering more percentage with less capital I will go for that one that's offering higher percentage with less capital. Remember if you borrow the large capital from bank you are still going to pay the interest rate and the bigger the funds you borrow the more interest you will pay. So the profit you make from the bigger capital won't be totally yours since you have to pay back your creditors.