Not only memecoin, recently launched projects have not had significant growth, so participating in the pre-markets will also pose many risks. So it will all depend on your risk tolerance as well as your knowledge in choosing which project to buy.
But in my opinion, investing in altcoins at this stage has a lot of risks, so I think you should not risk entering the pre-market or even rush to buy when they are first listed on the exchange. Looking at projects that are considered top potential such as STRK, ZK, ZRO...all have declined seriously since being listed on Binance until now.

Investing in altcoins is not a wise choice at the moment, instead let's focus on bitcoin more and I believe we still have time to buy altcoins, so don't rush.