If we look at it from this point of view, Bayer Leverkusen may have the highest rate of profitability. However, I wouldn't want to adopt this kind of betting tactic. I think betting should be based on a week-by-week analysis of performances and a detailed analysis of the injury situation of the players. Otherwise, I feel like I'm betting as if I'm putting the slot on autopilot. That would be an action out of my control and I don't like that. However, I have in the past advised a slot player on one of the online gambling sites that he could win more money if he bet on the weakest team in the league... 
Probably.Remember the team must win in order to get the reward, Leverkusen is undefeated, but they have draw for six times. But yeah 28x winning should able to cover all the losses and they're an underdog, not a team that people think they will become a champion and undefeated.
If you want to bet on weak team, better to bet draw instead of win, weak team is really rare to win.