Personally I haven't had a significant win that's enough to change my life but I have made little profits from gambling. There are people that made millions just form a single game but the thing is this isn't going to change your life automatically, having a big win isn't going to make you financially stable, your more has to make money for you, I'm Order for your wealth to stand the test of time you must you focus on making an investmen because its better to just buy something that's an asset
To me is all depends on the individual that hit the jackpot, sometimes some may lose that all because of the greed of wanting more while some may endup spending the money anyhow hoping to hit same jackpot again in long run (which is not guaranteed) . But one hitting the huge jackpot alone as already open alot way that can change ones lives, so it depends on how you use that money you won , some may decide to open a business that may serve as source of income in a long run .
Just like op said that he made use of his huge wins by starting a business which is a smart move , because that businesses will literally help in a long run.