There is so much for Real Madrid to lose this match, they just have to win it even though it's assure they have the body to make this 3 points or at worst, they can do draw because Atletico hasn't lose any match this season, they have draw and considering they will be hosting Real Madrid, they will have some bumps set ahead for Real Madrid and even in the past, their last few games didn't sit well for Real Madrid, their striker might also not be available due to a minor injury.
I think the faith of Osasuna is the same thing with the faith of Atletico Madrid. They are hosting the two big guys right in their home and they will be playing against them and these two need three points to max out in the top of the table. They have also not lose any match this season and so is Barcelona and Real Madrid, it's like we are having top matches this weekend and all of them are looking for the same thing, 3 points and nothing else.
Atletico Madrid has a pretty strong defense this season because in 7 matches they have only conceded 3 goals. I think the upcoming match when Atletico Madrid faces Real Madrid will of course be quite difficult to predict because there are several things that we can pay attention to, especially the performance of these two teams is quite good because they have not felt defeat and they also have quality players in their team.
On the other hand, Atletico Madrid will play at home which could raise the spirit of its players to perform better, especially Alvarez has found his best form, maybe he will be a threat to Real Madrid. However, in the depth of Real Madrid, of course they have many quality players like Mbappe so he will be the attention of Atletico Madrid defenders to stop his movement. If you look at the opportunities in the eighth week of La Liga, it is possible that one of them will experience their first defeat this season.