I can't believe Aston Villa isn't a big favorite in this match? their odds is @2.20, that's big considering Manchester United had a terrible history and the match will held in Villa Park. The only part Manchester United won is the head to head, they won 18 from 25 match, that's a big number, but it's just a history, not in the present.
Another interesting match is Tottenham vs Brighton, I think Tottenham will win since Brighton lost many important players.
Exactly my thoughts when I saw the odds

Aston Villa have almost twice as many points as United and by all statistical indicators they are better + they play at home. Fernandes will play as his red card has been cancelled but I think the odds were the same when he was expected to miss the game. Overall I have no explanation as to why the odds are like that.