Fenerbahce cannot be underestimated, they are quite better in the league, and they are drawn by the same team, who drew with Man United in the previous match.
I mean currently Fenerbahçe aren't playing that good. They have "The Special One" managing the team this season but for now they are struggling in multiple ways. Such as giving huge opportunities to their opponents and not being able to score comfortably. The defensive weaknesses just don't heal yet. Mourinho should find out a way with the current players he has or with transfers maybe.
And as for the offense, Dzeko is really old now. You can't expect him to play extra but he is still doing it. However not in the Europa League.
En-Nesyri is a huge disappointment. He misses chances unbelievably.