Betting on El classico isn't an easy task, most of the time we are going to end up with a lot of trouble and we shouldn't really approach this as something we need to care about because we shouldn't really care about any of this. I get how this could look a little bit different on paper because this is just another game where you see favourite, underdog, odds and all but this is a totally different type of game. Not only based on the talent level because this is the best two clubs of the league battling each other, but also there are politics involved as well, and the big history between these two teams.
So, this is definitely something most people will have hard time trying to guess what's going to happen. Obviously they managed to beach other many times to this day, even at the start of this season they had a game, so it is not really a crazy think to face off, but we are not going to know which one will win, so we need to be more careful about this.
Betting on derby matches or classic matches such as the Real Madrid vs Barcelona match is very risky. As a fan - you can bet on your own team regardless of whether it is Barcelona or Real Madrid. But don't have high expectations of winning so you don't rush into placing a big bet. Both teams have a chance to win - but for the first El Clasico I think Real Madrid is the favourite. Real Madrid are playing at home - usually they will play well and win the game, but anything can happen considering the injury storm that is currently plaguing them.