It is just how luck plays and coincidence works. If we would look at it, there's no definite correlation between being on vacation and placing your bet however it did happen to me before wherein I chose to play some games during a trip and had the same fate as OP. Other gamblers are also having the same suggestion not to, but for sure such thing doesn't happen all the time. I just put it as if you're lucky, then you'd win no matter what you are doing whether you're on a vacation or not. The only aspect I am agreeing not to gamble during days you're at rest is for you to focus spending your time without stressing on to other things you regularly do.
What if someone has lost a lot and then comes back again expecting to win back and that person is unlucky, then the defeat will double.
Inevitable, I believe. It is normal to lose in gambling anyway but atleast have some control with the amount you are betting. We may not have control of the outcome but we can limit the damage to our wallets in particular with gambling. I do make some 'testings' whenever I feel like gambling for the day; once I'm consistently losing then I make sure to take a pause and try the other day, than to force things out.