It's hard to let go when you believe the value will just keep growing. I think a lot of us hodlers are in the same boat, seeing it as a long-term investment or even something to pass down.
I can relate to this; however, I would say that one should at least have a target in mind. If the price hits that target, you should at least take a profit if you don't want to sell everything you hold because it isn't wise to keep holding when the market hits the top and starts declining.
In my opinion, those who sell when the market hits their target will have the opportunity to get more profit by buying again when the price corrects itself and starts going up. Now, if Bitcoin goes to $70k or something, one can buy again at that price if they had taken profit when it hit $99.5k.
I don't know if others will agree with me on this, but I feel having a target for taking profit and not getting greedy when the price reaches that point is a better approach than not doing it and regretting it later. Remember, taking profit means selling a portion and not everything you hold.