Taking a break will not easy for those who often playing gambling because they want to recover their losses and wins their money back. But they must keep trying to take a break for a while to reduces our emotion especially if we already lose too much money.
That is why we must have allocation for playing gambling and stick to our rules while we don't use all of that allocation money just to playing gambling for that day. We must remember that it is enough to playing gambling with that money and it is better if we can keep some money in our account that we can use to playing gambling in the other days.
It seems to me that the solution should be sought in the question itself, if the OP asks what to do if a huge loss occurs, then the obvious answer would be to exclude the possibility of a huge loss.
The bet amount should be small, or such that the loss does not make you feel bad. If you allow for such a thing that after a loss you will need some time to recover, then this is very bad, because the nervous system suffers a lot of damage, and this will have a bad effect not only on your finances, but also on your health, maybe not immediately but over time.