Yes, this is really an open ended question so there is no specific answer or advice for this question. Depending on the field, capital, knowledge, relationships...there are many things to consider.

In my opinion, let's prepare as best we can and always be ready to face the challenges that we encounter. No entrepreneur can succeed without facing and overcoming challenges and difficulties. And each person's path to success will have different obstacles, so being mentally prepared and having a strong will is the best thing we can do.
Seeking advice from experienced people is not necessarily bad, but as I said: everyone's path is different and there will be different ways of handling it, we should be ready to face and experience it ourselves to have the best lessons.